Strategies for increasing innovation in big pharmaceutical companies

Authors

  • ŠPELA BARBIČ University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia. , Univerza v Ljubljani, Fakulteta za farmacijo, Ljubljana, Slovenija.
  • LEA KNEZ Ludwig Maximilians University Munich, Germany. , Ludwig Maximilians University München, Nemčija.
  • ŠPELA KNEZ University of Ljubljana, Faculty of Biotechnology, Department of Genetics, Animal Biotechnology and Immunology, Slovenia. , Univerza v Ljubljani, Biotehniška fakulteta, Katedra za genetiko, animalno biotehnologijo in imunologijo, Slovenija. https://orcid.org/0000-0002-3538-2307 (unauthenticated)
  • TJAŠA MLAKAR University of Ljubljana, Faculty of Chemistry and Chemical Technology, Chair of Biochemistry, Ljubljana, Slovenia. , Univerza v Ljubljani, Fakulteta za kemijo in kemijsko tehnologijo, Katedra za biokemijo, Ljubljana,Slovenija.
  • SARA UHAN Charité - Universitätsmedizin Berlin, Department of Haematology, Oncology and Cancer Immunology, Germany. , Charité – Universitätsmedizin Berlin, Department of Hematology, Oncology and Cancer Immunology, Nemčija. https://orcid.org/0000-0003-4102-5063 (unauthenticated)
  • UROŠ VEZONIK University of Vienna, Institute of Organic Chemistry, Vienna, Austria. , University of Vienna, Institut of Organic Chemistry, Dunaj, Avstrija. https://orcid.org/0000-0003-3991-5323 (unauthenticated)
  • ZDENKO ČASAR University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia. , Univerza v Ljubljani, Fakulteta za farmacijo, Ljubljana, Slovenija. https://orcid.org/0000-0002-6689-3353 (unauthenticated)

DOI:

https://doi.org/10.18690/analipazuhd.9.1-2.95-123.2023

Keywords:

pharmaceutical companies, innovation, efficiency, research and development, SARS-CoV-2

Abstract

The overall technological, scientific and managerial progress of the last few decades is expected to be reflected in increased innovation and research efficiency in many entities, including large pharmaceutical companies. However, often the opposite can be observed. The efficiency of research and development (R&D), which can also be described as the input-output ratio, usually estimated by the number inhouse developed and launched medicines on the market or published scientific publications and granted patents, has been steadily declining in recent decades in the pharmaceutical industry. Nevertheless, especially in recent years many companies have shown successful resistance to this trend with an obvious increase in innovation, which among other things can be attributed to the improved financial efficiency and the design of new R&D models.

Author Biographies

  • ŠPELA BARBIČ, University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia., Univerza v Ljubljani, Fakulteta za farmacijo, Ljubljana, Slovenija.

    ŠPELA BARBIČ

    University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.

    E-mail: spelabarbi@gmail.com

  • LEA KNEZ, Ludwig Maximilians University Munich, Germany., Ludwig Maximilians University München, Nemčija.

    LEA KNEZ

    Ludwig Maximilians University Munich, Germany.

    E-mail: lea.knez07@gmail.com

  • ŠPELA KNEZ, University of Ljubljana, Faculty of Biotechnology, Department of Genetics, Animal Biotechnology and Immunology, Slovenia., Univerza v Ljubljani, Biotehniška fakulteta, Katedra za genetiko, animalno biotehnologijo in imunologijo, Slovenija.

    ŠPELA KNEZ

    University of Ljubljana, Faculty of Biotechnology, Department of Genetics, Animal Biotechnology and Immunology, Slovenia.

    E-mail: spela.knez@gmail.com

  • TJAŠA MLAKAR, University of Ljubljana, Faculty of Chemistry and Chemical Technology, Chair of Biochemistry, Ljubljana, Slovenia., Univerza v Ljubljani, Fakulteta za kemijo in kemijsko tehnologijo, Katedra za biokemijo, Ljubljana,Slovenija.

    TJAŠA MLAKAR

    University of Ljubljana, Faculty of Chemistry and Chemical Technology, Chair of Biochemistry, Ljubljana, Slovenia.

    E-mail: tjasamlakar.15@gmail.com

  • SARA UHAN, Charité - Universitätsmedizin Berlin, Department of Haematology, Oncology and Cancer Immunology, Germany., Charité – Universitätsmedizin Berlin, Department of Hematology, Oncology and Cancer Immunology, Nemčija.

    SARA UHAN

    Charité - Universitätsmedizin Berlin, Department of Haematology, Oncology and Cancer Immunology, Germany.

    E-mail: sara.uhan@charite.de

  • UROŠ VEZONIK, University of Vienna, Institute of Organic Chemistry, Vienna, Austria., University of Vienna, Institut of Organic Chemistry, Dunaj, Avstrija.

    UROŠ VEZONIK

    University of Vienna, Institute of Organic Chemistry, Vienna, Austria.

    E-mail: uros.vezonik@univie.ac.at

  • ZDENKO ČASAR, University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia., Univerza v Ljubljani, Fakulteta za farmacijo, Ljubljana, Slovenija.

    ZDENKO ČASAR

    University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.

    E-mail: zdenko.casar@ffa.uni-lj.si

Published

26.10.2023

How to Cite

BARBIČ, ŠPELA, KNEZ, L., KNEZ, ŠPELA, MLAKAR, T., UHAN, S., VEZONIK, U., & ČASAR, Z. (2023). Strategies for increasing innovation in big pharmaceutical companies. Anali PAZU HD, 9(1-2), 95-123. https://doi.org/10.18690/analipazuhd.9.1-2.95-123.2023

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