Ventricular arrhythmias and cardiac arrest in aconitine poisoning: a case report: Ventrikularne aritmije in srčni zastoj pri zastrupitvi z akonitinom: prikaz primera

Nino Cmor; Gašper  Razinger; Jure Fluher; Andrej Markota

doi:10.18690/actabiomed.269

Authors

Nino Cmor General Hospital Murska Sobota, Division of Cardiology , Splošna bolnišnica Murska Sobota, Interni oddelek, Kardiološki odsek Author
Gašper Razinger University Medical Centre Ljubljana, Center for Clinical Toxicology , Univerzitetni klinični center Ljubljana, Center za klinično toksikologijo in farmakologijo Author
Jure Fluher  University Medical Centre Maribor, University Division of Internal Medicine, Department of Intensive Internal Medicine;  University of Maribor, Faculty of Medicine , Univerzitetni klinični center Maribor, Klinika za interno medicino, Oddelek za intenzivno interno medicino; Univerza v Mariboru, Medicinska fakulteta Author
Andrej Markota  University Medical Centre Maribor, University Division of Internal Medicine, Department of Intensive Internal Medicine; University of Maribor, Faculty of Medicine , Univerzitetni klinični center Maribor, Klinika za interno medicino, Oddelek za intenzivno interno medicino; Univerza v Mariboru, Medicinska fakulteta Author

DOI:

https://doi.org/10.18690/actabiomed.269

Keywords:

ventricular arrhythmias, cardiac arrest, aconitine poisoning, cardiopulmonary resuscitation, amiodarone

Abstract

In traditional Chinese medicine, aconitum plants and roots are frequently used after extensive processing to treat various ailments in humans. However, use of a larger than recommended dose and inadequate processing increase the risk of aconitine poisoning. As a result of its particular mechanism of toxicity, aconitine poisoning can present with a variety of arrhythmias, including ventricular ectopy, ventricular tachycardia, ventricular fibrillation, and torsades de pointes. Meticulous arrythmia treatment is needed to restore sinus rhythm. We report a case of ventricular arrhythmias (VAs) induced by accidental aconitine poisoning. Our case highlights the efficacy of amiodarone in treating aconitine-induced VAs. To the best of our knowledge, this is one of the first described cases of aconitine-induced VAs in Europe. Clinicians should be aware of potential rare toxicological causes of malignant arrhythmias and consider toxicological screening in otherwise etiologically unexplained sudden cardiac arrest.

Author Biographies

Nino Cmor, General Hospital Murska Sobota, Division of Cardiology, Splošna bolnišnica Murska Sobota, Interni oddelek, Kardiološki odsek

Murska Sobota, Slovenia.
Gašper Razinger, University Medical Centre Ljubljana, Center for Clinical Toxicology, Univerzitetni klinični center Ljubljana, Center za klinično toksikologijo in farmakologijo

Ljubljana, Slovenia.
Jure Fluher,  University Medical Centre Maribor, University Division of Internal Medicine, Department of Intensive Internal Medicine;  University of Maribor, Faculty of Medicine , Univerzitetni klinični center Maribor, Klinika za interno medicino, Oddelek za intenzivno interno medicino; Univerza v Mariboru, Medicinska fakulteta

Maribor, Slovenia.
Andrej Markota,  University Medical Centre Maribor, University Division of Internal Medicine, Department of Intensive Internal Medicine; University of Maribor, Faculty of Medicine, Univerzitetni klinični center Maribor, Klinika za interno medicino, Oddelek za intenzivno interno medicino; Univerza v Mariboru, Medicinska fakulteta

Maribor, Slovenia.

Ventricular arrhythmias and cardiac arrest in aconitine poisoning: a case report

Ventrikularne aritmije in srčni zastoj pri zastrupitvi z akonitinom: prikaz primera

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