Acute pancreatitis in a patient with normal lipase: a case report

Akutni pankreatitis z normalnimi vrednostmi lipaze: prikaz primera

Authors

  • Tjaša Kitanovski General Hospital Novo mesto, Emergency center; University medical centre Ljubljana, Institute of Radiology , Splošna bolnišnica Novo mesto, Urgentni center; Univerzitetni klinični center Ljubljana, Klinični inštitut za radiologijo Author
  • Andrej Grahek General Hospital Novo mesto, Emergency center , Splošna bolnišnica Novo mesto, Urgentni center Author
  • Žan Garvas niversity of Ljubljana, Medical faculty , Univerza v Ljubljani, Medicinska fakulteta Author

DOI:

https://doi.org/10.18690/actabiomed.268

Keywords:

pancreatitis, negative lipase, alcoholism, necrotizing pancreatitis, supportive care

Abstract

This case report highlights the rare occurrence of acute pancreatitis in a patient exhibiting normal lipase levels. The patient presented to the emergency department with abdominal pain and fever. Laboratory tests indicated an acute inflammatory process but a negative lipase value. The diagnosis was established by a CT scan showing necrotizing pancreatic changes with elevated carbohydrate-deficient transferrin (CDT) levels, suggesting alcohol as the etiology. Management involved supportive care, aggressive fluid resuscitation, nutritional support, and empirical antibiotic therapy, which led to clinical improvement. This case emphasizes the importance of a comprehensive clinical assessment beyond standard biochemical markers in diagnosing and managing pancreatitis.

Author Biographies

  • Tjaša Kitanovski, General Hospital Novo mesto, Emergency center; University medical centre Ljubljana, Institute of Radiology, Splošna bolnišnica Novo mesto, Urgentni center; Univerzitetni klinični center Ljubljana, Klinični inštitut za radiologijo

    Slovenia.

  • Andrej Grahek, General Hospital Novo mesto, Emergency center, Splošna bolnišnica Novo mesto, Urgentni center

    Novo mesto, Slovenia.

  • Žan Garvas, niversity of Ljubljana, Medical faculty, Univerza v Ljubljani, Medicinska fakulteta

    Ljubljana, Slovenia.

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Published

12.07.2024

Issue

Section

Articles

How to Cite

Kitanovski, T., Grahek, A., & Garvas, Žan. (2024). Acute pancreatitis in a patient with normal lipase: a case report: Akutni pankreatitis z normalnimi vrednostmi lipaze: prikaz primera . Acta Medico-Biotechnica, 17(1), 52-56. https://doi.org/10.18690/actabiomed.268