Polyneuritis cranialis related to SARS-CoV-2 infection: a case report

Kranialni polinevritis, povezan z okužbo s SARS-CoV-2: prikaz primera

Authors

  • Peter Gradišnik University Medical Center Maribor, Department of Pediatrics , Univerzitetni klinični center Maribor, Klinika za pediatrijo Author
  • Andreja Osterc Koprivšek University Medical Center Maribor, Department of Pediatrics , Univerzitetni klinični center Maribor, Klinika za pediatrijo Author
  • Miha Rus University Clinical Center Maribor, Pediatric Intensive Care Unit , Univerzitetni klinični center Maribor, Enota za intenzivno nego in terapijo Author
  • Tanja Golli University Medical Centre Ljubljana, University Children's Hospital, Department of Pediatric Neurology , Univerzitetni klinični center Ljubljana Author
  • Hermina Damjan University Rehabilitation Institute image/svg+xml Author

DOI:

https://doi.org/10.18690/actabiomed.251

Keywords:

Polyneuritis cranialis, Miller Fisher syndrome, Multiple cranial nerve palsy, Coronavirus disease

Abstract

Purpose: Polyneuritis cranialis (PNC) is a less known regional variant of Guillain-Barré syndrome and has rarely been described in children. Here, we report a case of an adolescent, who became perilously ill following severe acute respiratory syndrome-coronavirus 2 infection.

Case report: A 15-year-old boy presented with acute multiple cranial nerve palsies. The presence of GQ1b antibodies and nerve conduction studies confirmed the diagnosis of PNC. The patient was treated with plasmapheresis and intravenous immunoglobulins, but clinical improvement was gradual and very slow.

Conclusion: PNC is a rare and severe neurologic condition that can be triggered by coronavirus infection.

Author Biographies

  • Peter Gradišnik, University Medical Center Maribor, Department of Pediatrics, Univerzitetni klinični center Maribor, Klinika za pediatrijo

    Maribor, Slovenia.

  • Andreja Osterc Koprivšek, University Medical Center Maribor, Department of Pediatrics, Univerzitetni klinični center Maribor, Klinika za pediatrijo

    Maribor, Slovenia.

  • Miha Rus, University Clinical Center Maribor, Pediatric Intensive Care Unit, Univerzitetni klinični center Maribor, Enota za intenzivno nego in terapijo

    Maribor, Slovenia.

  • Tanja Golli, University Medical Centre Ljubljana, University Children's Hospital, Department of Pediatric Neurology, Univerzitetni klinični center Ljubljana

    Ljubljana, Slovenia.

  • Hermina Damjan, University Rehabilitation Institute

    Ljubljana, Slovenia.

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Published

12.07.2023

Issue

Vol. 16 No. 1 (2023)

Section

Case report

License

Copyright (c) 2023 Peter Gradišnik, Andreja Osterc Koprivšek, Miha Rus, Tanja Golli, Hermina Damjan (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Gradišnik, P., Osterc Koprivšek, A., Rus, M., Golli, T. ., & Damjan, H. (2023). Polyneuritis cranialis related to SARS-CoV-2 infection: a case report: Kranialni polinevritis, povezan z okužbo s SARS-CoV-2: prikaz primera. Acta Medico-Biotechnica, 16(1), 53-56. https://doi.org/10.18690/actabiomed.251

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