Efficacy of metformin treatment in polycystic ovary syndrome

Učinkovitost zdravljenja sindroma policističnih jajčnikov z metforminom

Authors

  • Katja Jerenec University of Maribor, Faculty of Medicine , Univerza v Mariboru, Medicinska fakulteta Author
  • Maša Samojlenko University of Maribor, Faculty of Medicine , Univerza v Mariboru, Medicinska fakulteta Author
  • Ksenija Geršak University of Ljubljana, Faculty of Medicine, Department of Obstetrics and Gynaecology ; University Medical Centre Ljubljana , Univerza v Ljubljani, Medicinska fakulteta, Katedra za ginekologijo in porodništvo ; Univerzitetni klinični center Ljubljana Author
  • Polonca Ferk University of Maribor, Faculty of Medicine , Univerza v Mariboru, Medicinska fakulteta Author

DOI:

https://doi.org/10.18690/actabiomed.87

Keywords:

polycystic ovary syndrome, metformin, pharmacogenetics, personalized medicine

Abstract

Metformin is an oral antidiabetic drug with potentially beneficial effects in patients with polycystic ovary syndrome (PCOS). Different pharmacological responses to met- formin have been reported in PCOS patients, which may be attributable to various clinical, biochemical, genetic and other factors. Here, we have outlined a short review of the results from current clinical studies on metformin efficacy in PCOS patients. Additionally, preliminary results from a retrospective pharmacogenetic study by our group on a sample of Slovene PCOS patients are presented. Pharmacogenetics is an emerging science that should pro- vide options for individualized medicine, the future of healthcare.

Author Biographies

  • Katja Jerenec, University of Maribor, Faculty of Medicine, Univerza v Mariboru, Medicinska fakulteta

    Maribor, Slovenia.

  • Maša Samojlenko, University of Maribor, Faculty of Medicine, Univerza v Mariboru, Medicinska fakulteta

    Maribor, Slovenia.

  • Ksenija Geršak, University of Ljubljana, Faculty of Medicine, Department of Obstetrics and Gynaecology ; University Medical Centre Ljubljana, Univerza v Ljubljani, Medicinska fakulteta, Katedra za ginekologijo in porodništvo ; Univerzitetni klinični center Ljubljana

    Ljubljana, Slovenia.

  • Polonca Ferk, University of Maribor, Faculty of Medicine, Univerza v Mariboru, Medicinska fakulteta

    Assist. Prof., Maribor, Slovenia. E–mail: polonca.ferk@guest.arnes.si

Downloads

Published

27.11.2021

Issue

Vol. 6 No. 2 (2013)

Section

Articles

How to Cite

Jerenec, K., Samojlenko, M., Geršak, K., & Ferk, P. (2021). Efficacy of metformin treatment in polycystic ovary syndrome: Učinkovitost zdravljenja sindroma policističnih jajčnikov z metforminom. Acta Medico-Biotechnica, 6(2), 13-20. https://doi.org/10.18690/actabiomed.87

Most read articles by the same author(s)