Cell Physiology in Tissue Slices Studying Beta Cells in the Islets of Langerhans

Celična fiziologija v tkivnih rezinah - Preučevanje celic beta v Langerhansovih otočkih

Authors

  • Andraž Stožer University of Maribor, Faculty of Medicine, Institute of Physiology ; Centre for Open Innovations and Research, University of Maribor , Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo ; Center za odprte inovacije in raziskave Univerze v Mariboru Author
  • Jurij Dolenšek Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo , University of Maribor, Faculty of Medicine, Institute of Physiology Author
  • Maša Skelin Klemen University of Maribor, Faculty of Medicine, Institute of Physiology , Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo Author
  • Marjan Slak Rupnik University of Maribor, Faculty of Medicine, Institute of Physiology ; Centre for Open Innovations and Research, University of Maribor ; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins , Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo ; Center za odprte inovacije in raziskave Univerze v Mariboru ; Center odličnosti za integrirane pristope v kemiji in biologiji proteinov (CIPKeBiP) Author

DOI:

https://doi.org/10.18690/actabiomed.80

Abstract

Isolated endocrine cells have enabled the development of numerous methods to assess basic cellular architecture and define a significant part of the molecular machinery involved in cellular processes, such as excitability or the exocytotic release of hormones following cytosolic calcium increase. These efforts have generated consensus models explaining the activation or general operation of a particular cell type. The use of fresh tissue slices can go even further and uncover a series of emergent properties never explained orpredicted by consensus models. In this paper, we present a selection of our most important experimental findings in the beta cells of pancreatic tissue slices.

Author Biographies

  • Andraž Stožer, University of Maribor, Faculty of Medicine, Institute of Physiology ; Centre for Open Innovations and Research, University of Maribor, Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo ; Center za odprte inovacije in raziskave Univerze v Mariboru

    Maribor, Slovenia.

  • Jurij Dolenšek, Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo, University of Maribor, Faculty of Medicine, Institute of Physiology

    Maribor, Slovenia.

  • Maša Skelin Klemen, University of Maribor, Faculty of Medicine, Institute of Physiology, Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo

    Maribor, Slovenia.

  • Marjan Slak Rupnik, University of Maribor, Faculty of Medicine, Institute of Physiology ; Centre for Open Innovations and Research, University of Maribor ; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins, Univerza v Mariboru, Medicinska fakulteta, Inštitut za fiziologijo ; Center za odprte inovacije in raziskave Univerze v Mariboru ; Center odličnosti za integrirane pristope v kemiji in biologiji proteinov (CIPKeBiP)

    Prof. dr. Marjan Slak Rupnik, univ. dipl. biol., Maribor, Slovenia. E–mail: marjan.rupnik@um.si

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Published

27.11.2021

Issue

Vol. 6 No. 1 (2013)

Section

Articles

How to Cite

Stožer, A., Dolenšek, J., Skelin Klemen, M., & Slak Rupnik, M. (2021). Cell Physiology in Tissue Slices Studying Beta Cells in the Islets of Langerhans : Celična fiziologija v tkivnih rezinah - Preučevanje celic beta v Langerhansovih otočkih. Acta Medico-Biotechnica, 6(1), 20-32. https://doi.org/10.18690/actabiomed.80

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